{"id":59420,"date":"2026-10-25T23:17:10","date_gmt":"2026-10-25T21:17:10","guid":{"rendered":"https:\/\/melior.ee\/collagen-stimulators\/"},"modified":"2026-10-25T23:17:10","modified_gmt":"2026-10-25T21:17:10","slug":"collagen-stimulators","status":"publish","type":"post","link":"https:\/\/melior.ee\/en\/collagen-stimulators\/","title":{"rendered":"Collagen stimulators: Radiesse, PLLA and Ellans\u00e9 \u2013 how they work and when results show"},"content":{"rendered":"\n
Guide \u00b7 collagen stimulators<\/span>Melior Clinics \u00b7 updated 25.10.2026 \u00b7 4 min read<\/span><\/div>\n\n\n\n
In short<\/b>Collagen stimulators are injections of microparticles (PLLA, calcium hydroxylapatite, PCL) around which the skin gradually builds its own collagen. Final results usually show in 1\u20133 months<\/strong> (3\u20136 for PLLA) and typically last 12\u201318 months<\/strong>, up to 2 years with some products.<\/div>
1\u20133months<\/small><\/span>to the final result<\/span><\/div>
2\u20133sessions<\/small><\/span>typical PLLA course<\/span><\/div>
12\u201318months<\/small><\/span>typical duration, some up to 2 years<\/span><\/div>
\u20ac350<\/small><\/span>from, collagen stimulator at Melior<\/span><\/div><\/div>

Prices as of 25.10.2026<\/p><\/div>\n\n\n\n

Collagen stimulator vs filler vs Profhilo<\/h2>

Typical timings; the plan depends on area and product.<\/p>

<\/th>Collagen stimulator<\/th>Hyaluronic acid filler<\/th>Profhilo<\/th><\/tr><\/thead>
What it does<\/th>triggers your own collagen<\/td>adds volume at once<\/td>hydrates, supports elasticity<\/td><\/tr>
Volume<\/th>light or gradual<\/td>yes, at once<\/td>no<\/td><\/tr>
Results show<\/th>gradually over 1\u20133 months, PLLA 3\u20136<\/td>at once<\/td>in 5\u201310 days, full after the 2nd<\/td><\/tr>
Course<\/th>PLLA 2\u20133 sessions, others as planned<\/td>usually 1 session<\/td>2 sessions, about 4 weeks apart<\/td><\/tr>
Lasts<\/th>typically 12\u201318 months, some up to 2 years<\/td>typically 6\u201312 months<\/td>6\u201312 months<\/td><\/tr>
At Melior<\/th>HH PLLA, Lanluma, Radiesse, Ellans\u00e9<\/td>hyaluronic acid fillers<\/td>Profhilo, Profhilo Structura<\/td><\/tr><\/tbody><\/table><\/div><\/section>\n\n\n\n

Types of collagen stimulators: PLLA, Radiesse, Ellans\u00e9<\/h2>

Different particles \u2013 different speed and duration.<\/p>

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Poly-L-lactic acid (PLLA): HH PLLA, Lanluma<\/h3>

No instant volume. First changes at 6\u20138 weeks, the most at 3\u20136 months. A course of 2\u20133 sessions.<\/p><\/div><\/div>

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Calcium hydroxylapatite: Radiesse<\/h3>

Light support at once, final result in 2\u20133 months. Lasts up to 12\u201318 months.<\/p><\/div><\/div>

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Polycaprolactone (PCL): Ellans\u00e9<\/h3>

The gel adds volume at once, then particles trigger collagen: result in 1\u20133 months, lasting up to 2 years.<\/p><\/div><\/div>

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Collagen with hyaluronic acid: Karisma<\/h3>

A different approach, no particles: 2 sessions 30 days apart plus a booster at 4 months, lasting 6\u201312 months.<\/p><\/div><\/div><\/div><\/section>\n\n\n\n

\"A
First the specialist assesses the jawline and skin firmness<\/figcaption><\/figure><\/section>\n\n\n\n

When do collagen stimulator results show?<\/h2>

Tap a point on the timeline.<\/p>