Dissolving the filler syringe

What is hyaluronidase and how does it work?

Hyaluronidase is an enzyme that breaks down hyaluronic acid molecules. Most dermal fillers are hyaluronic acid gels that the body slowly breaks down on its own. Hyaluronidase speeds this up: injected into the area, it dissolves the gel, and the filler volume shrinks or disappears within a few days. It has no effect on fillers without hyaluronic acid, such as calcium hydroxylapatite or poly-L-lactic acid fillers, and it does not dissolve Ellansé or Biofiller, which are also used at Melior Clinics.

Filler dissolving at Melior Clinics

• Filler dissolving – hyaluronic acid filler in the lips, chin, cheekbones and under-eye area; a repeat session if needed.
• Price list – current prices for all treatments.

Dissolving is usually considered when a filler result looks unnatural or feels uncomfortable, when asymmetry or swelling has developed, when filler has migrated, or when old filler needs to be removed before a new treatment.

What happens during the treatment?

At the consultation, the specialist examines the area and discusses whether dissolving is needed and safe. It helps to know which filler was used and when. Previous allergies, especially to bee venom or protein-based products, must be mentioned, as well as blood thinners, which increase the risk of bruising. Alcohol is best avoided for 24 hours beforehand. Before hyaluronidase is injected, a skin test is done to check for sensitivity.

A small amount of hyaluronidase is injected directly where the filler sits; numbing cream can be used. The treatment takes up to 45 minutes. The effect usually shows within 2–3 days and is complete within 7 days. If not all of the filler dissolves the first time, the treatment can be repeated.

Who should not have it?

• allergy to hyaluronidase;
• acute skin inflammation or infection in the area;
• filler that does not contain hyaluronic acid;
• pregnancy or breastfeeding.

Medicines prescribed by your doctor are not stopped without their advice. The final decision is made by the specialist at the consultation.

After the treatment

Mild swelling, redness or itching at the injection site usually settles within a couple of days; a bruise is possible. On the day of treatment, make-up, exercise, sauna, pressure on the area and intense facial massage are best avoided. Alcohol is avoided for at least 48 hours.

Frequently asked questions

How long does hyaluronidase take to work?

Changes are often visible within 2–3 days, and the final result usually within 7 days. Large or dense amounts of filler may need more than one session.

Does filler dissolving hurt?

It can be slightly uncomfortable, but it is quick and usually well tolerated. Numbing cream can be used.

Does hyaluronidase dissolve your own hyaluronic acid?

The enzyme acts locally and briefly and does not damage the skin's natural structure; the body's own hyaluronic acid is constantly renewed.

When can I have filler again?

Waiting at least two weeks is usually advised, so the tissue can recover and the new result can be judged accurately.

The service is provided by Melior Clinics (Star Company OÜ, Estonian Health Board licence L04198), Liivalaia 53, Tallinn, 5th floor of the Stockmann department store.