Bioremodeling

What is bioremodelling and how does it work?

With age, skin loses hyaluronic acid, collagen and elastin and becomes drier, thinner and less firm. In bioremodelling, a product is injected into the skin or just beneath it, where it spreads evenly, hydrates and supports the skin's own collagen and elastin. Unlike a dermal filler, it creates no shaped volume: facial proportions stay the same, and skin quality changes over several weeks.

Bioremodelling treatments at Melior Clinics

• Profhilo® – low and high molecular weight hyaluronic acid for hydration and elasticity; face, neck, décolletage, hands.
• Profhilo® Structura – placed deeper, into subcutaneous fat; for a softened jawline and sagging.
• RRS® HA Long Lasting – hyaluronic acid, 15 amino acids and osmolytes; dry, tired skin.
• Seventy Hyal 2000 – concentrated hyaluronic acid (2000 kDa), amino acids and osmolytes; face or neck.
• Karisma – recombinant human collagen (RH Collagen®), hyaluronic acid and carboxymethylcellulose; face, neck, hands.
• Price list – current prices.

What happens during the treatment?

At the consultation, the specialist assesses your skin, health and medication and chooses the product. The skin is cleansed and disinfected; numbing cream can be used. Profhilo® is injected at five points on each side of the face, the other products with a fine needle into the upper skin layer or set points. A session takes about 30–45 minutes.

Usually 2 sessions are done about 4 weeks apart (sometimes one for RRS® HA Long Lasting, up to three for Seventy Hyal 2000); Karisma adds a booster after four months. The specialist sets the exact plan.

Who should not have it?

It is usually not done in case of:

• pregnancy or breastfeeding;
• allergy to hyaluronic acid or another ingredient, or a previous severe allergic reaction;
• inflammation, infection or cold sores in the area;
• fever, acute illness or a recent vaccination;
• an untreated or flaring autoimmune disease or other serious chronic illness;
• for Profhilo® Structura, also permanent filler or an implant in the area, or a tendency to keloid scars.

Blood thinners and other medicines must be mentioned to the specialist; medicines prescribed by your doctor are not stopped without their advice. The final decision is made by the specialist at the consultation.

After the treatment

Small bumps, needle marks, mild redness, swelling or tenderness usually settle within 1–3 days; a bruise is occasional. The area is not touched or washed for 2–3 hours, and make-up is avoided for 6–12 hours. Exercise, sauna, hot baths and alcohol are avoided for 24 hours, laser and peels for 1–2 weeks. SPF 50 is advised; sunbeds and tanning are avoided for a week.

Frequently asked questions

How long does Profhilo last?

First changes usually show in 5–10 days, the full effect 4–6 weeks after the second session. Results typically last 6–12 months, as with the other products (RRS® HA Long Lasting 6–9 months), depending on skin and lifestyle. Without repeat sessions, skin gradually returns to its previous state.

Profhilo vs Profhilo Structura: what is the difference?

Classic Profhilo® targets skin quality: hydration, elasticity and fine lines. Profhilo® Structura is placed deeper to support the facial contour and reduce sagging.

Bioremodelling vs biorevitalisation: what is the difference?

Both are hydrating skin boosters that add no volume. Biorevitalisation usually means many superficial micro-injections of non-cross-linked hyaluronic acid, while bioremodelling products such as Profhilo® spread slowly and also support skin density.

Does it hurt?

Most patients describe brief pinpricks. The needles are fine; numbing cream can be used.

The service is provided by Melior Clinics (Star Company OÜ, Estonian Health Board licence L04198), Liivalaia 53, Tallinn, 5th floor of the Stockmann department store.