Redermalization

What is redermalisation and how does it work?

Hyaluronic acid binds water and keeps skin soft and supple; with age and sun exposure its level falls, and skin looks dry and dull. In redermalisation, micro-injections place hyaluronic acid in the upper skin layers together with a substance involved in the cells' energy metabolism: succinic acid (succinate) in Xela Rederm, and NAD+ (nicotinamide adenine dinucleotide) with amino acids and peptides in HH NAD+ Complex. These are added to support skin metabolism, hydration and collagen production. The product forms small papules that are absorbed within a few days.

Redermalisation treatments at Melior Clinics

• HH NAD+ Complex – NAD+, hyaluronic acid, amino acids and peptides for tired, dull skin; face, neck, décolletage, hands.
• Xela Rederm – hyaluronic and succinic acid in two strengths; face including the eye area, neck, décolletage, hands.
• Price list – current prices.

What happens during the treatment?

At the consultation, the specialist reviews your skin, health, medication and recent cosmetic treatments and chooses the product. For Xela Rederm the strength is chosen too: 1.1% for younger, thin or sensitive skin and the eye area, 1.8% for mature skin or skin that has lost elasticity. After cleansing, numbing cream is usually applied and the product is injected as small papules. An HH NAD+ Complex session takes about 45–60 minutes.

A course is usual: 3 sessions of Xela Rederm or 2–4 of HH NAD+ Complex, 2–3 weeks apart. After recent fillers, botulinum injections, peels, laser or HIFU, a gap of 2–4 weeks is usually kept.

Who should not have it?

It is usually not done in case of:

• pregnancy or breastfeeding;
• allergy to hyaluronic acid, succinic acid or another ingredient;
• cold sores, inflammation, infection, a rash or wounds in the area;
• fever, a viral illness or feeling unwell;
• a flaring autoimmune disease or a severe chronic inflammatory disease;
• a bleeding disorder or regular use of blood thinners;
• cancer or active cancer treatment.

Medicines, including antibiotics, must be mentioned to the specialist; medicines prescribed by your doctor are not stopped without their advice. The final decision is made by the specialist at the consultation.

After the treatment

Papules usually settle within 1–3 days, and mild redness or swelling within 1–2 days. The skin is not touched or massaged. Make-up is fine the next day after HH NAD+ Complex; after Xela Rederm, cosmetics are avoided until the papules have gone. Alcohol, sauna, hot showers and intense exercise are avoided for 24 hours, and after Xela Rederm, sauna, sunbeds and exercise for 5–7 days. SPF 50 and a soothing cream recommended by the specialist are used.

Frequently asked questions

Redermalisation vs biorevitalisation: what is the difference?

Both use micro-injections of hyaluronic acid and add no volume. In biorevitalisation, hyaluronic acid is the main active ingredient, sometimes with amino acids or vitamins. Redermalisation products combine it with succinic acid or NAD+, which take part in the cells' energy metabolism.

When are results visible?

After Xela Rederm, skin usually feels tighter within 2–3 days, hydration improves within a week and overall skin condition changes over 3–4 weeks. With HH NAD+ Complex, first changes usually show after 5–7 days and build up during the course.

How long do results last?

This varies with skin condition, age and lifestyle, which is why maintenance sessions follow the course; for HH NAD+ Complex, usually every 2–3 months.

Does it hurt?

Most patients describe light stinging or pinpricks. Numbing cream is usually applied beforehand.

The service is provided by Melior Clinics (Star Company OÜ, Estonian Health Board licence L04198), Liivalaia 53, Tallinn, 5th floor of the Stockmann department store.